In this study we present some issues regarding the “network paradigm” considered to be nowadays the “third way” for the sustainable rural development. The sustainable rural development focuses on improving the livelihood in rural areas, respectively on satisfying the economic, social, cultural, and environmental necessities of the present generations, without hampering the chances of next generations to satisfy their needs. The success of sustainable agriculture and rural development depends not only on the individual aspirations, abilities and knowledge of the people, but mostly on the collective actions of the communities, as networks. The analysis of the knowledge-based networks from interdisciplinary approach helps to better understand the human behavior, the lifestyles, the way in which we are living and working together. Ultimately it helps us to identify and successfully overcome the challenges that we are facing nowadays.