The paper examines how to alleviate ergonomic hazard and techno-stress associated with the adoption of Information and Communication Technology (ICT). The University of Botswana was used as a case study. Personal observation and interviews were used to elicit information from the staff and students of the University. The rate of adoption of ICT was very high in the University. Most daily routines of academic and administrative duties were done through the Webct and network connection to mopipi.ub.bw. However, a serious gap was discovered in ergonomic practices because design of workstations did not perfectly match the standard expected to facilitate functionality and usability. It is imperative for the university to adopt the provisions of occupational health and safety policy to harmonize the environment, tools, and workers to achieve maximum efficiency and optimal performance.