In the era of globalization, the trend of university rankings gradually shifts from country-wide analyses to world-wide analyses. Relatively high analytical weightings on reputational surveys have led Quacquarelli Symonds (QS) World University Rankings to criticisms over the years. This study provides a comprehensive discussion of the indicators and weightings adopted in the QS survey. The article discusses several debates stirred in the academia on QS. Debates on this ranking system are presented in the study. Firstly, problems of return rate, as well as unequal distribution of returned questionnaires, have incurred regional bias. Secondly, some universities are listed in both domestic and international reputation questionnaires, but some others are listed only in the domestic part. Some universities were evaluated only by domestic respondents, limiting their performance of the ranking results. Thirdly, quite a few universities exhibit the same indicator scores or even full scores, rendering the assessment questionable. Lastly, enormous changes of single indicator scores suggest that the statistic data adopted by QS Rankings should be further questioned. Copyright The Author 2012. Published by Oxford University Press. All rights reserved. For Permissions, please email: email@example.com, Oxford University Press.