Screening opportunity bias in case-control studies of cancer screening

Stephen Duffy, Olsen, Anne-Helene, Rhian Gabe, Laszlo Tabar, Jane Warwick, Hilary Fielder, Laufey Tryggvadóttir and Olorunsola Agbaje

Journal of Applied Statistics, 2008, vol. 35, issue 5, pages 537-546

Abstract: In case-control evaluations of cancer screening, subjects who have died from the cancer in question (cases) are compared with those who have not (controls) with respect to screening histories. This method is subject to a rather subtle bias, among others, whereby the cases have greater opportunity to have been screened than the controls. In this paper, we propose a method of correction for this bias. We demonstrate its use on two case-control studies of mammographic screening for breast cancer.

Keywords: cancer screening; case-control study; opportunity bias (search for similar items in EconPapers)

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