Generalized least squares for trend estimation of summarized dose–response data
Nicola Orsini,
Rino Bellocco and
Sander Greenland Additional contact information Rino Bellocco: Karolinska Institutet
Sander Greenland: UCLA School of Public Health
Abstract:
This paper presents a command, glst, for trend estimation across different exposure levels for either single or multiple summarized case-control, incidence-rate, and cumulative incidence data. This approach is based on constructing an approximate covariance estimate for the log relative risks and estimating a corrected linear trend using generalized least squares. For trend analysis of multiple studies, glst can estimate fixed- and random-effects metaregression models. Copyright 2006 by StataCorp LP.