Resource costing for multinational neurologic clinical trials: methods and results

Kevin Schulman, Jennifer Burke, Michael Drummond, Linda Davies, Per Carlsson, Jans Gruger, Anthony Howard Harris, Carlo Lucioni, Ramon Gisbert, Ted Llana, Eric Tom, Bernard Bloom, Richard Willke and Henry Glick
Additional contact information
Kevin Schulman: Clinical Economics Research Unit, Georgetown University Medical Center, Washington, DC, USA, Postal: Clinical Economics Research Unit, Georgetown University Medical Center, Washington, DC, USA
Jennifer Burke: Clinical Economics Research Unit, Georgetown University Medical Center, Washington, DC, USA, Postal: Clinical Economics Research Unit, Georgetown University Medical Center, Washington, DC, USA
Michael Drummond: Centre for Health Economics, University of York, York, UK, Postal: Centre for Health Economics, University of York, York, UK
Linda Davies: Centre for Health Economics, University of York, York, UK, Postal: Centre for Health Economics, University of York, York, UK
Per Carlsson: Center for Medical Technology Assessment, Linkoping University, Sweden, Postal: Center for Medical Technology Assessment, Linkoping University, Sweden
Jans Gruger: SmithKline Beecham Pharma GmbH, Munich, Germany, Postal: SmithKline Beecham Pharma GmbH, Munich, Germany
Carlo Lucioni: Institute for Health Economics, Milan, Italy, Postal: Institute for Health Economics, Milan, Italy
Ramon Gisbert: SOIKOS, SL, Barcelona, Spain, Postal: SOIKOS, SL, Barcelona, Spain
Ted Llana: Covance Health Economics and Outcomes Services, West Sussex, UK, Postal: Covance Health Economics and Outcomes Services, West Sussex, UK
Eric Tom: Clinical Economics Research Unit, Georgetown University Medical Center, Washington, DC, USA, Postal: Clinical Economics Research Unit, Georgetown University Medical Center, Washington, DC, USA
Bernard Bloom: University of Pennsylvania, Division of General Internal Medicine, Philadelphia, PA, USA, Postal: University of Pennsylvania, Division of General Internal Medicine, Philadelphia, PA, USA
Richard Willke: Pharmacia & Upjohn, Inc., Kalamazoo, MI, USA, Postal: Pharmacia & Upjohn, Inc., Kalamazoo, MI, USA
Henry Glick: University of Pennsylvania, Division of General Internal Medicine, Philadelphia, PA, USA, Postal: University of Pennsylvania, Division of General Internal Medicine, Philadelphia, PA, USA

Health Economics, 1998, vol. 7, issue 7, pages 629-638

Abstract: We present the results of a multinational resource costing study for a prospective economic evaluation of a new medical technology for treatment of subarachnoid hemorrhage within a clinical trial. The study describes a framework for the collection and analysis of international resource cost data that can contribute to a consistent and accurate intercountry estimation of cost. Of the 15 countries that participated in the clinical trial, we collected cost information in the following seven: Australia, France, Germany, the UK, Italy, Spain, and Sweden. The collection of cost data in these countries was structured through the use of worksheets to provide accurate and efficient cost reporting. We converted total average costs to average variable costs and then aggregated the data to develop study unit costs. When unit costs were unavailable, we developed an index table, based on a market-basket approach, to estimate unit costs. To estimate the cost of a given procedure, the market-basket estimation process required that cost information be available for at least one country. When cost information was unavailable in all countries for a given procedure, we estimated costs using a method based on physician-work and practice-expense resource-based relative value units. Finally, we converted study unit costs to a common currency using purchasing power parity measures. Through this costing exercise we developed a set of unit costs for patient services and per diem hospital services. We conclude by discussing the implications of our costing exercise and suggest guidelines to facilitate more effective multinational costing exercises. © 1998 John Wiley & Sons, Ltd.

Date: 1998
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Persistent link: http://EconPapers.repec.org/RePEc:wly:hlthec:v:7:y:1998:i:7:p:629-638

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