A Double-Blind Placebo-Controlled Trial of Acediprol (Valproate Sodium) For Global Severity in Child Autism Spectrum Disorders
Aliyev Na and
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Aliyev Na: Department of psychiatry and addiction, Azerbaijan State Advanced Training Institute, Azerbaijan
Aliyev Zn: Department of psychiatry, Azerbaijan Medical University, Azerbaijan
Online Journal Of Neurology And Brain Disorders, 2018, vol. 2, issue 1, 93-97
The effects of Valproate sodium and placebo on global severity were compared in Child Autism Spectrum Disorders (ASD). Childs with ASDs were enrolled in a 12-week double-blind placebo-controlled Valproate sodium trial. Fifty were randomly assigned to Valproate sodium (n=50) or placebo (n=50). The initial dose of Valproate sodium for children is 15mg/kg, then increases by 5-10mg/kg every week to 20-50mg/kg. Children are given 5% syrup (Sirupus Valproate sodium 5%), 1 ml 50mg. Repetitive behaviors were measured with the Clinical Global Impression (CGI) improvement scale.
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JEL-codes: R00 Z0 (search for similar items in EconPapers)
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