Meta-analytical Integration of Diagnostic Accuracy Studies in Stata

North American Stata Users' Group Meetings 2007 from Stata Users Group

Abstract: This presentation will demonstrate how to perform diagnostic meta-analysis using midas , a user-written macro. midas is is comprehensive program of statistical and graphical routines for undertaking meta-analysis of diagnostic test performance in Stata. Primary data synthesis is performed within the bivariate generalized linear mixed modeling framework. Model specification, estimation and prediction are carried out with gllamm (Rabe-Hesketh et.al, spherical adaptive quadrature). Using the estimated coefficients and variance-covariance matrices, midas calculates the summary operating sensitivity and specificity (with confidence and prediction ellipses) in SROC space. Summary likelihood and odds ratios with relevant heterogeneity statistics are provided. midas facilitates extensive statistical and graphical data synthesis and exploratory analyses of unobserved heterogeneity, covariate effects, publication bias and subgroup analyses. Bayes' nomograms, likelihood ratio matrices and conditional probability plots may be obtained and used to guide clinical decision-making.

New Economics Papers: this item is included in nep-dcm
Date: 2007-08-30

Downloads: (external link)
http://repec.org/nasug2007/BD-nasug2007.ppt presentation slides (application/x-mspowerpoint)
http://repec.org/nasug2007/midas.ado program code (text/plain)
http://repec.org/nasug2007/midas_examples9.ado sample job (version 9.x) (text/plain)
http://repec.org/nasug2007/midas_examples.ado sample job (text/plain)
http://repec.org/nasug2007/midas.hlp help file (text/plain)
http://repec.org/nasug2007/midas.sthlp help file (text/plain)
http://repec.org/nasug2007/midas_example_data.dta sample data file (application/x-stata)

Related works:
Working Paper: Meta-analytical Integration of Diagnostic Accuracy Studies in Stata (2007)
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