A Novel Micro RNA Feedback Loop of High Mobility Group Protein A1a in Regulating Estrogen Receptor Alpha Alternative Splicing

Kenji Ohe, Yoshihiro Harada, Yuta Horita, Hiroyoshi Harada, Hiroki Terai, Masayoshi Mori, Yusuke Murata, Munechika Enjoji and Kenji Ashida
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Munechika Enjoji: Department of Pharmacotherapeutics, Faculty of Phamaceutical Sciences, Fukuoka University, Fukuoka city, Japan
Kenji Ashida: Division of Endocrinology and Metabolism, Department of Internal Medicine, Kurume University School of Medicine, Kurume city, Japan

Biomedical Journal of Scientific & Technical Research, 2018, vol. 11, issue 1, 8327-8332

Abstract: The hERα gene is known for its major role in estrogen dependent growth of breast cancer. ERα positivity is a hallmark in treating these cancers. Though there are many isoforms reported for hERα, the splicing regulation...

Keywords: Biomedical Sciences; Biomedical Research; Technical Research; ERα Gene; Hmga1a; Non Coding Exon; Splicing Regulation; Microrna; Tamoxifen Resistance (search for similar items in EconPapers)
Date: 2018
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Persistent link: https://EconPapers.repec.org/RePEc:abf:journl:v:11:y:2018:i:1:p:8327-8332

DOI: 10.26717/BJSTR.2018.10.002058

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