Molecular Docking, Synthesis, in Silico and in vitro Screening of Substituted Aryl Ureido Analogues as BACE1 Inhibitors to target Alzheimer’s Disease

Archana S Gurjar, Vinay Velingkar, Vincenza Andrisano and Angela D Simone
Additional contact information
Archana S Gurjar: Department of Pharmaceutical Chemistry, India
Vinay Velingkar: HK College of Pharmacy, India
Angela D Simone: Department for Life Quality Studies, India

Biomedical Journal of Scientific & Technical Research, 2018, vol. 11, issue 4, 8679-8684

Abstract: BACE1 plays critical role in the formation of neurotoxic β-amyloid (Aβ) peptides in brain and so is regarded as an ideal drug design target for Alzheimer’s disease...

Keywords: Biomedical Sciences; Biomedical Research; Technical Research; BACE1; Aryl Ureido Analogues; Molecular Docking; in Silico ADME; In Vitro; FRET Assay (search for similar items in EconPapers)
Date: 2018
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Persistent link: https://EconPapers.repec.org/RePEc:abf:journl:v:11:y:2018:i:4:p:8679-8684

DOI: 10.26717/BJSTR.2018.11.002140

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