Direct Access to New Gem-Difluorinated Pyrido[1,2-a] Pyrimidine-2-one Systems

Ranin Kawtharani, Mohamed Abarbri, Ranin Kawtharani, Mirvat Elmasri, Ali Hachem and Khalil Cherry
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Mohamed Abarbri: Laboratoire de Physico-Chimie des Matériaux et des Electrolytes pour l’Energie (PCM2E), France
Ali Hachem: Laboratoire de Chimie Médicinale et de Produit naturels, (LCMPN) Lebanon
Khalil Cherry: Laboratoire Matériaux, Catalyse, Environnement et Méthodes Analytiques (MCEMA), Lebanon

Biomedical Journal of Scientific & Technical Research, 2019, vol. 16, issue 3, 12063-12080

Abstract: Efficient method for the synthesis of gem-difluorinated pyrido[1,2-a]pyrimidine- 2-ones using addition/heterocyclization followed by Heck and Suzuki cross coupling reactions is reported...

Keywords: Biomedical Sciences; Biomedical Research; Technical Research; Gem-Difluorinated Pyrido[1; 2-a]Pyrimidine-2-Ones; 2-Aminopyridines; Gem-Difluorinated Alkynes; Heck Reaction; Suzuki Reaction (search for similar items in EconPapers)
Date: 2019
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Persistent link: https://EconPapers.repec.org/RePEc:abf:journl:v:16:y:2019:i:3:p:12063-12080

DOI: 10.26717/BJSTR.2019.16.002859

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