MTHFR677T and 1298C Play Independent but Opposite Effects in Stroke - Additive Co-Effect of two Intragenic Alleles

Shuo Li, Yuming Xu, Edward W Randell, Fei-Yu Han, Hong Zheng, Liwen Zou and Ya-Gang Xie
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Yuming Xu: Department of Neurology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, PR China
Fei-Yu Han: Disciplines of Laboratory Medicine, Memorial University of Newfoundland, St. John’s, NL, Canada
Hong Zheng: Department of Biology, Faculty of Medicine, Zhengzhou University, Zhengzhou, Henan, P. R. China
Liwen Zou: Department of Mathematics and statistics, University of New Brunswick, Saint John, NB, Canada
Ya-Gang Xie: Disciplines of Laboratory Medicine, Memorial University of Newfoundland, St. John’s, NL, Canada

Biomedical Journal of Scientific & Technical Research, 2019, vol. 17, issue 1, 12563-12569

Abstract: The MTHFR677C>T variant has been repeatedly shown to associate with cardiovascular disease (CVD) including stroke...

Keywords: Biomedical Sciences; Biomedical Research; Technical Research; MTHFR Gene Variants; Ischemic Stroke; Association; Additive Co-Effect of Intragenic Allele-Allele Interaction (search for similar items in EconPapers)
Date: 2019
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Persistent link: https://EconPapers.repec.org/RePEc:abf:journl:v:17:y:2019:i:1:p:12563-12569

DOI: 10.26717/BJSTR.2019.17.002954

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