Force Degradation Study of Rizatriptan Benzoate by RpHPLC Method and Characterization of Degraded Product

Pritam S Jain, Harshal P Chaudhari, Gayatri B Patil and Sanjay J Surana
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Sanjay J Surana: RC Patel Institute of Pharmaceutical Education and Research, India

Biomedical Journal of Scientific & Technical Research, 2017, vol. 1, issue 5, 1456-1462

Abstract: he objective of the work was to study the degradation behavior of rizatriptan benzoate under different ICH recommended stress conditions by HPLC, and to establish a validated stability indicating LC assay method. Rizatriptan benzoate was subjected to stress conditions of hydrolysis and oxidation decomposition. Extensive degradation was found to occur in acidic medium...

Keywords: Biomedical Sciences; Biomedical Research; Technical research Rizatriptan Benzoate; Rp-Hplc; Validation; Purity Evaluation; Degradation Product (search for similar items in EconPapers)
Date: 2017
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Persistent link: https://EconPapers.repec.org/RePEc:abf:journl:v:1:y:2017:i:5:p:1456-1462

DOI: 10.26717/BJSTR.2017.01.000461

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