Selective Conventional Transarterial Chemoembolization with Oxaliplatin Increases Tumor Exposure Compared to Systemic Administration in a Rabbit Model of Hepatocellular Carcinoma

A Dencausse, E Laveissiere, Idee Jm, C Factor, P Robert, A Seron, C Corot and S Ballet
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C Corot: Guerbet, Research & Innovation Division, BP 57400, 95943 Roissy-Charles de Gaulle cedex, France
S Ballet: Guerbet, Medical Affairs Division, BP 57400, 95943 Roissy-Charles de Gaulle cedex, France

Biomedical Journal of Scientific & Technical Research, 2021, vol. 37, issue 5, 29824-29835

Abstract: To compare the pharmacokinetics and biodistribution of hepatic artery infusion of oxaliplatin emulsified in Lipiodol (cTACE) versus intravenous (IV) infusion in a rabbit model of HCC....

Keywords: Pharmacokinetics; Plasma; Tumor; Histology; Hepatocellular Carcinoma; Thrombocytopenia; Neurotoxicity Liver Cancer; Pharmacological Efficacy; Chemoembolization (search for similar items in EconPapers)
Date: 2021
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Persistent link: https://EconPapers.repec.org/RePEc:abf:journl:v:37:y:2021:i:5:p:29824-29835

DOI: 10.26717/BJSTR.2021.37.006065

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