A New Method for In Vivo Targeted Gene Transfer into Oligodendrocytes using Adenoviral and HIV Vectors

Koichi Miyake, Noriko Miyake and Takashi Shimada
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Koichi Miyake: Department of Gene Therapy, Nippon Medical School, Tokyo, Japan
Takashi Shimada: Department of Biochemistry and Molecular Biology, Nippon Medical School, Tokyo, Japan

Biomedical Journal of Scientific & Technical Research, 2021, vol. 39, issue 3, 31379-31385

Abstract: To achieve oligodendrocyte (OL)-specific gene transfer, we applied a two-step method in which target cells were first engineered to express CD4 in a tissue-specific manner using adenoviral....

Keywords: Targeted Gene Transfer; Retroviral; Oligodendricytes; Receptor; Adenoviral Vector; Myelin; HIV Vector; Non-Dividing Cells; Ketamine; Serum (search for similar items in EconPapers)
Date: 2021
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Persistent link: https://EconPapers.repec.org/RePEc:abf:journl:v:39:y:2021:i:3:p:31379-31385

DOI: 10.26717/BJSTR.2021.39.006306

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