Efficacy and Safety of Guluronic Acid (G2013) in a Randomized, Controlled Phase II Clinical Trial on Patients with Multiple Sclerosis

Payam Saadat, Masoomeh Noorbakhsh, Nahid Beladi Moghadam, Dmitry Babarykin, Galina Smirnova, Soheil Najaf, Mostafa Hosseini and Abbas Mirshafiey
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Payam Saadat: Mobility Impairment Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran
Masoomeh Noorbakhsh: Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
Nahid Beladi Moghadam: Department of Neurology, Imam Hossein Hospital, Shahid Beheshti University of Medical Science, Tehran, Iran
Dmitry Babarykin: Institute of Innovative Biomedical Technology Ltd, Riga, Latvia
Galina Smirnova: Institute of Innovative Biomedical Technology Ltd, Riga, Latvia
Soheil Najaf: Institute of Innovative Biomedical Technology Ltd, Riga, Latvia
Mostafa Hosseini: Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
Abbas Mirshafiey: Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran

Biomedical Journal of Scientific & Technical Research, 2022, vol. 47, issue 5, 38859-38869

Abstract: The α-L-guluronic acid (G2013) as a new anti-inflammatory drug with immunomodulatory property, patented (PCT/EP2017/067920), showed positive effects in experimental models of multiple sclerosis (MS). In this clinical trial, our aim was to evaluate 6 months efficacy and safety outcomes in MS treated patients with guluronic acid compared to the conventional drug.

Keywords: Journals on Medical Drug and Therapeutics; Journals on Emergency Medicine; Physical Medicine and Rehabilitation; Journals on Infectious Diseases Addiction Science and Clinical Pathology; Open Access Clinical and Medical Journal; Journals on Biomedical Science; List of Open Access Medical Journal; Journals on Biomedical Engineering; Open Access Medical Journal; Biomedical Science Articles; Journal of Scientific and Technical Research (search for similar items in EconPapers)
Date: 2022
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Persistent link: https://EconPapers.repec.org/RePEc:abf:journl:v:47:y:2022:i:5:p:38859-38869

DOI: 10.26717/BJSTR.2022.47.007552

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