The Role of Pancreatic Stellate Cells in the Repair of Pancreatic Injury

Zhou Wence
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Zhou Wence: The Second Hospital of Lanzhou University, China

Biomedical Journal of Scientific & Technical Research, 2023, vol. 49, issue 3, 40657-40664

Abstract: When pancreatic tissue is damaged by external force or inflammation, it initiates its own repair process. Like most tissue damage repair, the repair process of pancreatic injury also includes the repair of cellular and interstitial components. The repair of cell components is achieved through cell division and proliferation, while the repair of interstitial components is mainly completed through the secretion of extracellular matrix (ECM). As the main cellular component of pancreatic tissue, pancreatic stellate cells (PSCs) participate in the secretion of ECM and the differentiation and proliferation of other pancreatic parenchymal cells through various pathways. A large number of studies have confirmed that the activation of PSC plays an important role in the repair of pancreatic injury. Based on a large number of literature study, this paper summarizes the current research progress on the mechanism of PSC in the repair of pancreatic injury, in order to provide new directions and ideas for the basic research and clinical diagnosis and treatment of pancreatic injury

Keywords: Journals on Medical Drug and Therapeutics; Journals on Emergency Medicine; Physical Medicine and Rehabilitation; Journals on Infectious Diseases Addiction Science and Clinical Pathology; Open Access Clinical and Medical Journal; Journals on Biomedical Science; List of Open Access Medical Journal; Journals on Biomedical Engineering; Open Access Medical Journal; Biomedical Science Articles; Journal of Scientific and Technical Research (search for similar items in EconPapers)
Date: 2023
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Persistent link: https://EconPapers.repec.org/RePEc:abf:journl:v:49:y:2023:i:3:p:40657-40664

DOI: 10.26717/BJSTR.2023.49.007800

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