A Case of Pseudopheochromocytoma- Quetiapine Induction of Norepinephine

T Patrick Jensen
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T Patrick Jensen: Medical Director of Consult and Liaison Psychiatry Service and Senior Behavioral Unit, Covenant Health, USA

Biomedical Journal of Scientific & Technical Research, 2023, vol. 49, issue 4, 40934-40940

Abstract: An acutely altered elderly female presented following orthopedic repair. She was afebrile, normotensive, but tachycardic. Once declared medically stable, she was transferred to a geropsychiatric facility for stabilization of acute psychosis. Her psychosis remained refractory to treatment, and she was noted to have an elevated ionized calcium. Plasma metanephrines were evaluated, followed by confirmatory urinary metanephrines. Both were significantly elevated. Negative imaging following this laboratory workup prompted consideration of possible tertiary causes. It was determined that the patient was likely experiencing a phenomenon known as Pseudopheochromocytoma, induced by Seroquel, of which she was on the maximum recommended dose. Once Seroquel was discontinued, the patient’s autonomic instability stabilized. Although a pheochromocytoma was not completely excluded by a PET scan in this case, its existence was unlikely, especially given autonomic improvement following Seroquel taper and discontinuation.

Keywords: Journals on Medical Drug and Therapeutics; Journals on Emergency Medicine; Physical Medicine and Rehabilitation; Journals on Infectious Diseases Addiction Science and Clinical Pathology; Open Access Clinical and Medical Journal; Journals on Biomedical Science; List of Open Access Medical Journal; Journals on Biomedical Engineering; Open Access Medical Journal; Biomedical Science Articles; Journal of Scientific and Technical Research (search for similar items in EconPapers)
Date: 2023
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Persistent link: https://EconPapers.repec.org/RePEc:abf:journl:v:49:y:2023:i:4:p:40934-40940

DOI: 10.26717/BJSTR.2023.49.007843

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