Two Fatal Cases Involving Synthetic Cannabinoid, 5F-AKB-48

Abdulaziz A Aldlgan
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Abdulaziz A Aldlgan: Security Forces Hospital, Ministry of Interior, Riyadh, Saudi Arabia

Biomedical Journal of Scientific & Technical Research, 2023, vol. 49, issue 5, 41018-41020

Abstract: The usage of new psychoactive substance (NPS), particularly synthetic cannabinoids (SCs), has blasted at extraordinary pace in recent years universally. A quite number of these drugs has more toxic consequence than Δ 9 -tetrahydrocannabinol (THC). Due to their enhanced strength and uncontrolled dose, these drugs might cause critical clinical consequences. The toxicological finding of SCs from two postmortem cases in Scotland with suspected intake of SCs, is presented in this research. Liquid chromatography-tandem mass spectrometry (LC–MS/MS) was used to analyze the samples after a basic liquid extraction. A total of twenty SCs were included in this method; 5F- AKB-48 was positive in both cases. Although there is inadequate evidence to link blood 5F-AKB- 48 concentration to effect in additional to the lack of other rational interpretations, the drugs should be counted as the causative case of death based on history and circumstances, as well as toxicological data. Consequently, SCs appear to be more toxic than cannabis because of their increased potency and dose, which might result to overdose and catastrophic clinical effects. Under specific conditions, the acute toxic effects may contribute to death.

Keywords: Journals on Medical Drug and Therapeutics; Journals on Emergency Medicine; Physical Medicine and Rehabilitation; Journals on Infectious Diseases Addiction Science and Clinical Pathology; Open Access Clinical and Medical Journal; Journals on Biomedical Science; List of Open Access Medical Journal; Journals on Biomedical Engineering; Open Access Medical Journal; Biomedical Science Articles; Journal of Scientific and Technical Research (search for similar items in EconPapers)
Date: 2023
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Persistent link: https://EconPapers.repec.org/RePEc:abf:journl:v:49:y:2023:i:5:p:41018-41020

DOI: 10.26717/BJSTR.2023.49.007859

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