Stem Cell Therapy for Regeneration of Radiated Salivary Glands

Ola M Ezzatt
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Ola M Ezzatt: Department of Oral Medicine, Periodontology and Oral Diagnosis, Faculty of Dentistry, Ain-Shams University, Cairo, Egypt

Biomedical Journal of Scientific & Technical Research, 2023, vol. 49, issue 5, 41123-41128

Abstract: Radiation used in the treatment of head and neck cancer causes significant damage to the salivary glands and a loss of salivary function. Current therapies for radiation-induced salivary hypofunction aimed to stimulate residual functional salivary gland tissues and treat the symptoms of xerostomia without restoring the lost tissue. Several research strategies are emerging, aimed at regenerating salivary glands damaged by radiation via either gene therapy or by transplantation of stem cells. This concise review focuses on cell-based therapeutic strategies for regeneration of irradiated salivary gland (SG) tissues and discuss the possible regenerative potentials and applications of GMSCs in this context.

Keywords: Journals on Medical Drug and Therapeutics; Journals on Emergency Medicine; Physical Medicine and Rehabilitation; Journals on Infectious Diseases Addiction Science and Clinical Pathology; Open Access Clinical and Medical Journal; Journals on Biomedical Science; List of Open Access Medical Journal; Journals on Biomedical Engineering; Open Access Medical Journal; Biomedical Science Articles; Journal of Scientific and Technical Research (search for similar items in EconPapers)
Date: 2023
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Persistent link: https://EconPapers.repec.org/RePEc:abf:journl:v:49:y:2023:i:5:p:41123-41128

DOI: 10.26717/BJSTR.2023.49.007876

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