Clinical Application of Therapeutic Bispecific Antibodies

Girum Tefera Belachew
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Girum Tefera Belachew: Department of Biotechnology, College of Natural and Computational Sciences, Debre Birhan University, Ethiopia

Biomedical Journal of Scientific & Technical Research, 2023, vol. 49, issue 5, 41145-41153

Abstract: Bispecific antibodies (BsAbs) have been developed, with one antigen-binding site coordinated against the CD3 receptor (which activates cytotoxic T lymphocytes) and the other against specific antigens found on cancer cells (CD19, CD20, CD33, CD123, HER2, epithelial cell adhesion molecule [EpCAM], BCMA, CEA, and others). Bispecific antibodies (BsAbs) are unique immunological constructs that frequently recognize two distinct target antigens from multiple proteins.

Keywords: Journals on Medical Drug and Therapeutics; Journals on Emergency Medicine; Physical Medicine and Rehabilitation; Journals on Infectious Diseases Addiction Science and Clinical Pathology; Open Access Clinical and Medical Journal; Journals on Biomedical Science; List of Open Access Medical Journal; Journals on Biomedical Engineering; Open Access Medical Journal; Biomedical Science Articles; Journal of Scientific and Technical Research (search for similar items in EconPapers)
Date: 2023
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Persistent link: https://EconPapers.repec.org/RePEc:abf:journl:v:49:y:2023:i:5:p:41145-41153

DOI: 10.26717/BJSTR.2023.49.007880

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