A Blood Biomarker Panel Recommended for Personalized Prediction, Prognosis and Prevention of Rheumatoid Arthritis

Radka Fuchsova
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Radka Fuchsova: Department of Immunochemistry Diagnostics, University Hospital and Faculty of Medicine in Pilsen, Charles University, Czech Republic

Biomedical Journal of Scientific & Technical Research, 2023, vol. 50, issue 2, 41580-41583

Abstract: Rheumatoid arthritis (RA) is the most common chronic autoimmune joint disease affecting synovial tissue in multiple joints. The course of RA can be very heterogeneous and patients with the same diagnosis can present with different symptoms and outcomes as well as the possible development of irreversible joint damage leading to loss of function. Evidence suggests that RA develops in 3 phases: an asymptomatic period of genetic risk, a pre-clinical period in which RA-related antibodies can be detected, and a clinical phase with the clinical symptoms of inflammatory arthritis. Early detection of RA and the availability of biologic agents have markedly improved outcomes in these patients [1]. At present, composite indices (mostly DAS28, Disease Activity Index) are used to monitor the activity of the disease. They include clinical parameters (tender and swollen joints), and two laboratory parameters of inflammation: C reactive protein (CRP) and erythrocyte sedimentation rate parameter (ESR). The disadvantage of these scores is.

Keywords: Journals on Medical Drug and Therapeutics; Journals on Emergency Medicine; Physical Medicine and Rehabilitation; Journals on Infectious Diseases Addiction Science and Clinical Pathology; Open Access Clinical and Medical Journal; Journals on Biomedical Science; List of Open Access Medical Journal; Journals on Biomedical Engineering; Open Access Medical Journal; Biomedical Science Articles; Journal of Scientific and Technical Research (search for similar items in EconPapers)
Date: 2023
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Persistent link: https://EconPapers.repec.org/RePEc:abf:journl:v:50:y:2023:i:2:p:41580-41583

DOI: 10.26717/BJSTR.2023.50.007938

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