Methanol Fraction of Ethanol Extract of Dialium Guineense Stem Bark Mitigates STZ-Induced Oxidative Stress in Rat Liver

Abu Od
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Abu Od: Department of Biochemistry, Faculty of Life Sciences, University of Benin, Nigeria

Biomedical Journal of Scientific & Technical Research, 2023, vol. 51, issue 2, 42594-42600

Abstract: The present study investigated the effect of methanol fraction of ethanol extract of Dialium guineense (MEDG) stem bark on streptozotocin (STZ)-induced oxidative stress in rat liver. Male albino rats of Wistar strain (n = 25, mean weight = 215 ± 15 g) were randomly assigned to five groups (5 rats/group): normal control, diabetic control, metformin, MEDG [200 mg/kg body weight (bwt)] and MEDG (300 mg/kg bwt) groups. Diabetes mellitus was induced in the rats via intraperitoneal injection of 50 mg/kg bwt STZ.

Keywords: Journals on Medical Drug and Therapeutics; Journals on Emergency Medicine; Physical Medicine and Rehabilitation; Journals on Infectious Diseases Addiction Science and Clinical Pathology; Open Access Clinical and Medical Journal; Journals on Biomedical Science; List of Open Access Medical Journal; Journals on Biomedical Engineering; Open Access Medical Journal; Biomedical Science Articles; Journal of Scientific and Technical Research (search for similar items in EconPapers)
Date: 2023
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Persistent link: https://EconPapers.repec.org/RePEc:abf:journl:v:51:y:2023:i:2:p:42594-42600

DOI: 10.26717/BJSTR.2023.51.008085

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