The Cytotoxicity of Metformin and Misoprostol Overwhelms their Antiviral Activity in SARS-CoV-2-Infected Vero-E6 Cell Culture

Sherine Abdelmissih
Additional contact information
Sherine Abdelmissih: Department of Medical Pharmacology, Faculty of Medicine, Kasr Al-Ainy, Cairo University, Cairo, Egypt

Biomedical Journal of Scientific & Technical Research, 2023, vol. 52, issue 4, 43887-43896

Abstract: Coronavirus disease 2019 (COVID-19) due to the acute respiratory syndrome coronavirus2 (SARS-CoV-2) caused a global health crisis that called for re-purposing of many medications. Both the implication of diabetes mellitus (DM) in increasing the risk of COVID-19-associated respiratory complications, together with the claims about the involvement of acidic pH in exacerbating acute lung injury as well as SARS-CoV-2 invasion, growth, and replication, guided our interest towards possible efficacy of antidiabetic and anti-peptic ulcer medications in such condition.

Keywords: Journals on Medical Drug and Therapeutics; Journals on Emergency Medicine; Physical Medicine and Rehabilitation; Journals on Infectious Diseases Addiction Science and Clinical Pathology; Open Access Clinical and Medical Journal; Journals on Biomedical Science; List of Open Access Medical Journal; Journals on Biomedical Engineering; Open Access Medical Journal; Biomedical Science Articles; Journal of Scientific and Technical Research (search for similar items in EconPapers)
Date: 2023
References: Add references at CitEc
Citations:

Downloads: (external link)
https://biomedres.us/pdfs/BJSTR.MS.ID.008281.pdf (application/pdf)
https://biomedres.us/fulltexts/BJSTR.MS.ID.008281.php (text/html)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:abf:journl:v:52:y:2023:i:4:p:43887-43896

DOI: 10.26717/BJSTR.2023.52.008281

Access Statistics for this article

Biomedical Journal of Scientific & Technical Research is currently edited by Robert Thomas

More articles in Biomedical Journal of Scientific & Technical Research from Biomedical Research Network+, LLC
Bibliographic data for series maintained by Angela Roy ().