Kinetics of α2-Macroglobulin in Rats with GentamicinInduced Acute Severe Renal Failure

Takashi Kuribayashi
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Takashi Kuribayashi: Laboratory of Immunology, School of Life and Environmental Science, Azabu University, Japan

Biomedical Journal of Scientific & Technical Research, 2023, vol. 52, issue 5, 44038-44043

Abstract: The kinetics of α2-macroglobulin (α2M) were evaluated in rats with acute severe renal failure. This renal failure was induced by repeated subcutaneous injections of gentamicin at a dose of 80 or 120 mg/kg for 10 days. Twenty-two male Sprague-Dawley rats were divided into two groups for two experiments. Turpentine oil was intramuscularly injected at a dosage of 0.2 mL/kg body weight at 2 days after finishing the injections of gentamicin. The serum concentrations of α2M were then measured by enzyme-linked immunosorbent assay.

Keywords: Journals on Medical Drug and Therapeutics; Journals on Emergency Medicine; Physical Medicine and Rehabilitation; Journals on Infectious Diseases Addiction Science and Clinical Pathology; Open Access Clinical and Medical Journal; Journals on Biomedical Science; List of Open Access Medical Journal; Journals on Biomedical Engineering; Open Access Medical Journal; Biomedical Science Articles; Journal of Scientific and Technical Research (search for similar items in EconPapers)
Date: 2023
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Persistent link: https://EconPapers.repec.org/RePEc:abf:journl:v:52:y:2023:i:5:p:44038-44043

DOI: 10.26717/BJSTR.2023.52.008301

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