Correlation between Serum Interleukin-8, Interleukin-6 Levels, and the Response to Anti-PD-1/PD-L1 Inhibitor in Patients with Malignant Tumors- A Prospective Observational Study

Xi Tang
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Xi Tang: Oncology Department, Huadong Hospital, Fudan University, China

Biomedical Journal of Scientific & Technical Research, 2023, vol. 53, issue 1, 44332-44339

Abstract: The programmed cell death (PD-1) receptor and its ligand (PDL1) are involved in an important immune checkpoint that helps keep the body›s immune responses in check [1]. Cancer cells can express PD-L1 and PD-L2, which can inhibit immune-modulatory T-cell activation and facilitate disease progression by targeting the PD-1 receptor [2-4]; thus, blocking either PD-1 or PD-L1 can prevent PD-1 activation, attenuating the immune tolerance and improving T cell-mediated killing of cancer cells [5,6].

Keywords: Journals on Medical Drug and Therapeutics; Journals on Emergency Medicine; Physical Medicine and Rehabilitation; Journals on Infectious Diseases Addiction Science and Clinical Pathology; Open Access Clinical and Medical Journal; Journals on Biomedical Science; List of Open Access Medical Journal; Journals on Biomedical Engineering; Open Access Medical Journal; Biomedical Science Articles; Journal of Scientific and Technical Research (search for similar items in EconPapers)
Date: 2023
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Persistent link: https://EconPapers.repec.org/RePEc:abf:journl:v:53:y:2023:i:1:p:44332-44339

DOI: 10.26717/BJSTR.2023.53.008349

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