Tofacitinib Treatment in Refractory Systemic Lupus Erythematosus with Shrinking Lung Syndrome- A Case-Based Review

Yongmei Han
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Yongmei Han: Department of Rheumatology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, China

Biomedical Journal of Scientific & Technical Research, 2024, vol. 54, issue 2, 45779-45786

Abstract: Shrinking Lung Syndrome (SLS) is a rare pulmonary complication of Systemic Lupus Erythematosus (SLE), which mainly manifests as dyspnea, pleural chest pain, and restrictive ventilation dysfunction, with or without an elevated hemi-diaphragm. Currently, there is no unified diagnostic criteria for SLS. SLS is a diagnosis of exclusion and can be diagnosed only in the absence of interstitial, alveolar and pulmonary vascular disease. The treatment is based on high-dose glucocorticoids and immunosuppressants. Here, we report a case of a 35-year-old woman who was diagnosed with SLE in 2008. Four years later, she was diagnosed with SLS due to chest pain, dyspnea, cough, and restrictive ventilatory dysfunction.

Keywords: Journals on Medical Drug and Therapeutics; Journals on Emergency Medicine; Physical Medicine and Rehabilitation; Journals on Infectious Diseases Addiction Science and Clinical Pathology; Open Access Clinical and Medical Journal; Journals on Biomedical Science; List of Open Access Medical Journal; Journals on Biomedical Engineering; Open Access Medical Journal; Biomedical Science Articles; Journal of Scientific and Technical Research (search for similar items in EconPapers)
Date: 2024
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Persistent link: https://EconPapers.repec.org/RePEc:abf:journl:v:54:y:2023:i:2:p:45779-45786

DOI: 10.26717/BJSTR.2024.54.008533

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