Medication Related Osteonecrosis of Jaw (MRONJ)- A Case Report of the Synergistic Effect of Pentoxifyllin and Tocopherol (PENTO Protocol) in Treatment of MRONJ

Aya Mostafa
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Aya Mostafa: Department of oral medicine and periodontology, College of dentistry, Ain shams University, Egypt

Biomedical Journal of Scientific & Technical Research, 2024, vol. 54, issue 4, 46101-46106

Abstract: Osteonecrosis of jaw is a condition in which bone cells die due to various causes. It has several types one of them is Medication related osteonecrosis of the jaw (MRONJ). MRONJ significantly affects the patient’s quality of life and leads to a significant percentage of mortality. The treatment of osteonecrosis can be conservative, which aims to be beneficial for the patient’s quality of life, and surgical, which involves debridement of the necrotic bone. This article describes a case of a 60 years old female patient with necrotic segment of her mandibular jaw with no pain and a history of taking hormonal drug after stopping chemotherapy for 1 year. We have laid down a new non-surgical well tolerated treatment modality with minimal side effects.

Keywords: Journals on Medical Drug and Therapeutics; Journals on Emergency Medicine; Physical Medicine and Rehabilitation; Journals on Infectious Diseases Addiction Science and Clinical Pathology; Open Access Clinical and Medical Journal; Journals on Biomedical Science; List of Open Access Medical Journal; Journals on Biomedical Engineering; Open Access Medical Journal; Biomedical Science Articles; Journal of Scientific and Technical Research (search for similar items in EconPapers)
Date: 2024
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Persistent link: https://EconPapers.repec.org/RePEc:abf:journl:v:54:y:2024:i:4:p:46101-46106

DOI: 10.26717/BJSTR.2024.54.008575

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