Results of Genetic Studies of Adolescents with Idiopathic Hypogonadotropic Hypogonadism

Mavlonov U Kh Alieva DA, Mavlonov U Kh, Saydakhmedova Mu, Khudaybergenov Sh A, Boboev Kt and Urmanova Yu M
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Urmanova Yu M: Republican Specialized Scientific and Practical Medical Center of Endocrinology of the Ministry of Health of the Republic of Uzbekistan named after academician. Y.H. Turakulova, Department of Neuroendocrinology, Tashkent Pediatric Medical Institute, Department of Endocrinology, Pediatric Endocrinology, Department of Surgical Diseases, Bukhara Regional Endocrinological Dispensary, Republican Specialized Scientific and Practical Medical Center for Hematology, Republic of Uzbekistan

Biomedical Journal of Scientific & Technical Research, 2024, vol. 54, issue 5, 46474-46479

Abstract: Gonadotropin releasing hormone (GnRH) is the main hormone of the reproductive endocrine system. The existence of central hormones regulating reproduction was postulated a century ago [1]. In 1910, Crowe et al. [2]. demonstrated that disruption of the hypothalamic-pituitary connection in dogs prevents the onset of puberty. Subsequent studies led to the hypothesis that the pituitary gland is controlled by the hypothalamic factor [3-6]. However, it was not until 1971 that the amino acid sequence of GnRH was determined after extraction from the hypothalamus of thousands of pigs and sheep by the groups of Chally and Guillemin [7,8].

Keywords: Journals on Medical Drug and Therapeutics; Journals on Emergency Medicine; Physical Medicine and Rehabilitation; Journals on Infectious Diseases Addiction Science and Clinical Pathology; Open Access Clinical and Medical Journal; Journals on Biomedical Science; List of Open Access Medical Journal; Journals on Biomedical Engineering; Open Access Medical Journal; Biomedical Science Articles; Journal of Scientific and Technical Research (search for similar items in EconPapers)
Date: 2024
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Persistent link: https://EconPapers.repec.org/RePEc:abf:journl:v:54:y:2024:i:5:p:46474-46479

DOI: 10.26717/BJSTR.2024.54.008624

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