The Influence of Protein Loading in Emptied Yeast on its Bactericidal and Anticancer Effectiveness

Nawal Abd El-Baky, Mona M Sharaf and Amro A Amara
Additional contact information
Amro A Amara: Protein Research Department, Genetic Engineering and Biotechnology Research Institute (GEBRI), City of Scientific Research and Technological Applications (SRTA-City), Egypt

Biomedical Journal of Scientific & Technical Research, 2024, vol. 55, issue 1, 46542-46548

Abstract: While yeasts were employed for delivery of drugs, active RNA or DNA, they were in minor cases utilized in delivery of certain antigenic proteins. The loading of bioeffective proteins inside emptied cells can preserve their structure and bioefficiency. In the present work, loaded lactoferrin inside emptied yeast was assayed for bactericidal and anticancer effectiveness after loading and compared with free protein. Its bactericidal efficiency was assayed against S. aureus, S. typhi, K. pneumonia, S. sonnei, P. vulgaris, S. marcescens, and E. coli. Its cytotoxicity was checked on human skin fibroblast (HSF) and potential anticancer impact on epidermoid skin carcinoma of human (A-431).

Keywords: Journals on Medical Drug and Therapeutics; Journals on Emergency Medicine; Physical Medicine and Rehabilitation; Journals on Infectious Diseases Addiction Science and Clinical Pathology; Open Access Clinical and Medical Journal; Journals on Biomedical Science; List of Open Access Medical Journal; Journals on Biomedical Engineering; Open Access Medical Journal; Biomedical Science Articles; Journal of Scientific and Technical Research (search for similar items in EconPapers)
Date: 2024
References: Add references at CitEc
Citations:

Downloads: (external link)
https://biomedres.us/pdfs/BJSTR.MS.ID.008635.pdf (application/pdf)
https://biomedres.us/fulltexts/BJSTR.MS.ID.008635.php (text/html)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:abf:journl:v:55:y:2024:i:1:p:46542-46548

DOI: 10.26717/BJSTR.2024.55.008635

Access Statistics for this article

Biomedical Journal of Scientific & Technical Research is currently edited by Robert Thomas

More articles in Biomedical Journal of Scientific & Technical Research from Biomedical Research Network+, LLC
Bibliographic data for series maintained by Angela Roy ().