Long-Term Cryopreservation of an Autologous Immunocomplex of Dendritic Cells and Cancer Antigen (HiDCV-OS1) that Stimulates Antitumor Immunity Against Chemotherapy-Resistant Ovarian Cancer

Masao Sasai, Kyoso Ishida, Tomoyuki Nishikawa, Chin Yang Chang, Jiro Fujita, Hiroki Higashihara, Keigo Osuga, Toshihiro Nakajima, Kenjiro Sawada, Tadashi Kimura, Yasufumi Kaneda and Kazuma Sakura
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Masao Sasai: Frontier of Regenerative Medicine, Graduate School of Medicine, Osaka University, Japan
Kyoso Ishida: Toyonaka Municipal Hospital, Japan
Tomoyuki Nishikawa: Department of Device Application for Molecular Therapeutics, Graduate School of Medicine, Osaka University, Japan
Chin Yang Chang: Department of Gene & Stem Cell Regenerative Therapy, Graduate School of Medicine, Osaka University, Japan
Jiro Fujita: Department of Hematology and Oncology, Graduate School of Medicine, Osaka University, Japan
Hiroki Higashihara: Center of Interventional Radiology, Osaka University Hospital, Japan
Keigo Osuga: Department of Diagnostic Radiology, Osaka Medical and Pharmaceutical University, Japan
Toshihiro Nakajima: Immunomedicine, Inc., Japan
Kenjiro Sawada: Division of Obstetrics and Gynecology, Graduate School of Medicine, Osaka University, Japan
Tadashi Kimura: Sakai City Medical Center, Japan
Yasufumi Kaneda: Administration Bureau, Osaka University, Japan
Kazuma Sakura: Respiratory Center, Osaka University Hospital, Japan

Biomedical Journal of Scientific & Technical Research, 2024, vol. 56, issue 2, 47914-47917

Abstract: In recent years, therapies that use cellular products made from autologous tissues for medical treatment have been developed. Although novel treatments for ovarian cancer, such as a PARP inhibitor, have been developed and the prognosis has improved, for the relapse of ovarian cancer, efficient treatments are not developed for the relapse yet. We started a clinical trial of autologous cell processed products (HiDCVOS1), which were made from ovarian cancer cells and dendritic cells by using hemagglutinating virus of Japan envelope (HVJ-E).

Keywords: Journals on Medical Drug and Therapeutics; Journals on Emergency Medicine; Physical Medicine and Rehabilitation; Journals on Infectious Diseases Addiction Science and Clinical Pathology; Open Access Clinical and Medical Journal; Journals on Biomedical Science; List of Open Access Medical Journal; Journals on Biomedical Engineering; Open Access Medical Journal; Biomedical Science Articles; Journal of Scientific and Technical Research (search for similar items in EconPapers)
Date: 2024
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Persistent link: https://EconPapers.repec.org/RePEc:abf:journl:v:56:y:2024:i:2:p:47914-47917

DOI: 10.26717/BJSTR.2024.56.008830

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