Impacts of Polymorphic Alterations in the ASXL1 Gene in the Context of Acute Myeloid Leukemia

Anna Julia Piva, Juliana Dario, Davi Zanoni Valente, Regiane Priscila Ratti Sartori and Larissa Teodoro Rabi
Additional contact information
Larissa Teodoro Rabi: Department of Biomedicine, Nossa Senhora do Patrocínio University Center (CEUNSP), Brazil

Biomedical Journal of Scientific & Technical Research, 2024, vol. 58, issue 5, 50944-50951

Abstract: Acute myeloid leukemia (AML) is characterized by abnormal proliferation of immature myeloid cells. Although it has no specific factor for development, it may be linked to genetic inheritance, lifestyle or exposure to toxicity. Bioinformatics analyses enable the screening and identification of diagnostic or prognostic biomarkers for AML. The ASXL1 gene is associated with hematopoietic cell differentiation, mutations and polymorphisms in the sequence that are considered risk factors for the development of AML, often associated with poor prognosis and low survival rate.

Keywords: Journals on Medical Drug and Therapeutics; Journals on Emergency Medicine; Physical Medicine and Rehabilitation; Journals on Infectious Diseases Addiction Science and Clinical Pathology; Open Access Clinical and Medical Journal; Journals on Biomedical Science; List of Open Access Medical Journal; Journals on Biomedical Engineering; Open Access Medical Journal; Biomedical Science Articles; Journal of Scientific and Technical Research (search for similar items in EconPapers)
Date: 2024
References: Add references at CitEc
Citations:

Downloads: (external link)
https://biomedres.us/pdfs/BJSTR.MS.ID.009219.pdf (application/pdf)
https://biomedres.us/fulltexts/BJSTR.MS.ID.009219.php (text/html)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:abf:journl:v:58:y:2024:i:5:p:50944-50951

DOI: 10.26717/BJSTR.2024.58.009219

Access Statistics for this article

Biomedical Journal of Scientific & Technical Research is currently edited by Robert Thomas

More articles in Biomedical Journal of Scientific & Technical Research from Biomedical Research Network+, LLC
Bibliographic data for series maintained by Angela Roy ().