Studies on the Influence of Liriopes Radix Nanovesicles on Inflammatory and Immune-Related Factors in Oral Squamous Cancer

Shuangyu Hu, Zhenxia Wei, Xiaoping Su and Xuanping Huang
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Zhenxia Wei: Department of Oral and Maxillofacial Surgery, College & Hospital of Stomatology, Guangxi Medical University, China
Xiaoping Su: Guangxi Key Laboratory of Oral and Maxillofacial Rehabilitation and Reconstruction, Guangxi Clinical Research Center for Craniofacial Deformity, Guangxi Medical University, China
Xuanping Huang: Department of Oral and Maxillofacial Surgery, College & Hospital of Stomatology, Guangxi Medical University, China

Biomedical Journal of Scientific & Technical Research, 2024, vol. 59, issue 3, 51649-51658

Abstract: The LRNVs were characterized and quantified. The uptake of nanovesicles was observed by laser con- focal scanning microscopy. Plate cloning experiments, transwell experiments and apoptosis experiments were carried out to explore the effect of LRNVs on OSCC in vitro. The expressions of Bad, Bax, Bcl-2, MMP9 and NFκB were detected by western blot. A xenograft model of oral cancer in C57BL/6J mice was constructed and the DiR- stained LRNVs was administered to mice via intraperitoneal injection to observe the fluorescence aggregation in the abdomen of mice.

Keywords: Journals on Medical Drug and Therapeutics; Journals on Emergency Medicine; Physical Medicine and Rehabilitation; Journals on Infectious Diseases Addiction Science and Clinical Pathology; Open Access Clinical and Medical Journal; Journals on Biomedical Science; List of Open Access Medical Journal; Journals on Biomedical Engineering; Open Access Medical Journal; Biomedical Science Articles; Journal of Scientific and Technical Research (search for similar items in EconPapers)
Date: 2024
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Persistent link: https://EconPapers.repec.org/RePEc:abf:journl:v:59:y:2024:i:3:p:51649-51658

DOI: 10.26717/BJSTR.2024.59.009313

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