Evaluation of Electrocardiographic Activity (ECG) and Blood Pressure Changes in Experimental Animal Models Treated with Doxorubicin and Hesperidin Co-Administration

Etah Etah Nkanu, Sandra Lungu, Moses Nyerinda and Esther George
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Moses Nyerinda: Department of Physiology, Faculty of Medicine and Surgery, Lusaka Apex Medical University, Zambia
Esther George: Department of Physiology, Faculty of Basic Medical Sciences, University of Cross River State, Calabar, Nigeria

Biomedical Journal of Scientific & Technical Research, 2024, vol. 59, issue 4, 51824-51833

Abstract: The use of Doxorubicin as a common drug for the treatment of cancer can not be overemphasized. Despite its therapeutic effect, its clinical impact is compromised due to its high doses for effective treatment resulting in a side effect such as cardiotoxicity. Hesperidin, a citrus bioflavonoid with a wide range of biological activities including antioxidant, anti-inflammatory, anticancer, and cardio protective effects, may be protective.

Keywords: Journals on Medical Drug and Therapeutics; Journals on Emergency Medicine; Physical Medicine and Rehabilitation; Journals on Infectious Diseases Addiction Science and Clinical Pathology; Open Access Clinical and Medical Journal; Journals on Biomedical Science; List of Open Access Medical Journal; Journals on Biomedical Engineering; Open Access Medical Journal; Biomedical Science Articles; Journal of Scientific and Technical Research (search for similar items in EconPapers)
Date: 2024
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Persistent link: https://EconPapers.repec.org/RePEc:abf:journl:v:59:y:2024:i:4:p:51824-51833

DOI: 10.26717/BJSTR.2024.59.009342

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