TNFα Therapy – Is Personalization of Treatment Selection Possible?

Irina Momcheva and Ivan Kazmin
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Ivan Kazmin: Rheumatology Department, University Hospital Burgas, Bulgaria

Biomedical Journal of Scientific & Technical Research, 2025, vol. 60, issue 2, 52328-52332

Abstract: TNF-α is a important inflammatory protein, involved in the pathogenesis of many immune-mediated diseases. It activates various cellular processes, including inflammation, cell death, and the production of other inflamma- tory molecules. TNF-α Interacts with two Types of Receptors (TNFR1 and TNFR2), triggering different cellular responses. Activation of TNFR1 typically leads to inflammation, while TNFR2 may have anti-inflammatory ef- fects.

Keywords: Journals on Medical Drug and Therapeutics; Journals on Emergency Medicine; Physical Medicine and Rehabilitation; Journals on Infectious Diseases Addiction Science and Clinical Pathology; Open Access Clinical and Medical Journal; Journals on Biomedical Science; List of Open Access Medical Journal; Journals on Biomedical Engineering; Open Access Medical Journal; Biomedical Science Articles; Journal of Scientific and Technical Research (search for similar items in EconPapers)
Date: 2025
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Persistent link: https://EconPapers.repec.org/RePEc:abf:journl:v:60:y:2025:i:2:p:52328-52332

DOI: 10.26717/BJSTR.2025.60.009416

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