Making Sense of Orthodontic Genetics: A Simplified Conceptual Overview

Rakesh M. Sharma
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Rakesh M. Sharma: Department Dental Studies, Faculty of Applied Biology, BHU, Varanasi, India

Inventum Biologicum: An International Journal of Biological Research, 2023, vol. 3, issue 1, 24-27

Abstract: In oral cavity, disturbances due to genetic alterations may range from lack of tooth development to morphological defects. Due to technical advances in genetic engineering and molecular biology, valuable information regarding dentofacial growth could be studied in detailed manner. This helps us to explain the aetiology and pathogenesis of many dentofacial disorders. The success in treatment lies first in determining the aetiology of tooth anomalies and finally differentiating the effect of genes and environment on the orofacial diseases of that particular individual. Types of Genetic Factors influence numerous biological processes including orthodontic tooth movement (OTM), external apical root resorption, and problems with tooth formation and/or eruption. Therefore, when a clinician has a good understanding of the genetic factors that influence OTM and some of the genetically influenced problems associated with OTM, treatment outcomes can be improved for many of their patients.

Keywords: Craniofacial defect; Homeoboxgenes; Orthodontic Tooth Movement (search for similar items in EconPapers)
Date: 2023
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