Herbal Interventions for Urolithiasis: A Systematic Evaluation of Efficacy and Safety

M.R. Eromedogane, J.H. Okantu and E.L. Ebawun
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M.R. Eromedogane: Department of Health and Wellbeing, Faculty of Biomedicine, Delta State University, Asaba Campus, Nigeria
J.H. Okantu: Department of Health and Wellbeing, Faculty of Biomedicine, Delta State University, Asaba Campus, Nigeria
E.L. Ebawun: Department of Health and Wellbeing, Faculty of Biomedicine, Delta State University, Asaba Campus, Nigeria

Inventum Biologicum: An International Journal of Biological Research, 2023, vol. 3, issue 3, 78-82

Abstract: Urolithiasis, the process of stone formation in the kidney, bladder, and/or urethra (urinary tract), is a condition affecting 12% of the global population, as per the World Health Organization (WHO). The prevalence is higher in males, ranging from 70-81%, compared to females, where it ranges from 47-60%, resulting in a gender ratio of 2.4:1. Traditional plants contain diverse chemical constituents that exert positive effects on lithiasis through various molecular mechanisms. Several medicinal plants, including Moringa oleifera, Crataeva magna, Aerva javanica, Peperomia tetraphylla, Terminalia bellirica, Ipomoea eriocarpa, Punica granatum, Hibiscus rosasinensis, Costus spiralis, and Herniaria hirsuta, exhibit antiurolithiatic effects. This review aims to present information and highlight current trends in research on medicinal plants with antiurolithiatic activity. The insights provided in this review may aid in the identification of lead compounds or herbal products responsible for antiurolithiatic activity.

Keywords: Urolithiasis; Molecular mechanism; Traditional plants; Lead compound (search for similar items in EconPapers)
Date: 2023
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