Metabolic Regulation at the Molecular Level: Investigating Intracellular Routes and Clinical Consequences in the Regression of Atherosclerosis and the Optimisation of Cardiovascular Health

Gurjant Singh
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Gurjant Singh: M.Sc Botany, Department of Botanical and Environmental Sciences, Guru Nanak Dev University, Amritsar, Punjab, India

Inventum Biologicum: An International Journal of Biological Research, 2025, vol. 5, issue 3, 26-35

Abstract: The conventional therapy for atherosclerosis, marked by the buildup of arterial plaque that constricts and hardens the arteries, involves managing elevated blood pressure and cholesterol levels. Recent research indicates that fasting can effectively repair atherosclerosis. This review investigates the mechanisms by which fasting influences atherosclerosis, analyses clinical data, outlines fasting procedures, considers patient demographics, and discusses the clinical implications. The clinical data illustrating the efficacy of fasting in inhibiting atherosclerosis progression is analysed, with the molecular impacts of fasting on metabolism, cellular function, and inflammation. This study evaluates the feasibility, duration, and outcomes of several fasting protocols, including time-restricted eating and intermittent fasting, across diverse patient populations. The evaluation also addresses implementation aspects, including safety in clinical environments, monitoring, and patient education. This review contributes to the understanding of fasting’s therapeutic potential in preventing atherosclerosis and improving cardiovascular health.

Keywords: Atherosclerosis; Fasting protocols; Cardiovascular health; Intermittent fasting; Metabolic regulation (search for similar items in EconPapers)
Date: 2025
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