Emblica Officinalis Protects Against Sodium Arsenite Induced Hepatotoxicity & Nephrotoxicity In Rats

Arun Kumar, Raj Bala, Farida Bano, Ranjit Kumar and Mohammad Ali

International Journal of Sciences, 2015, vol. 4, issue 03, 47-55

Abstract: Arsenic in the present times has caused lots of health hazards to humans. In developing countries like Bangladesh and India the high prevalence of contamination, the isolation and poverty of the rural population, and the high cost and complexity of arsenic removal systems have imposed a programmatic and policy challenge on an unprecedented scale. Although in India, Arsenic poisoning in ground water in Gangetic belt especially the districts adjoining the river Ganges right from Eastern Uttar Pradesh, Bihar to West Bengal are the major problem of concern as due to which major health related problems are arising. To combat the present problem, a pre-clinical study was done on Charles foster rats. They were treated with Sodium arsenite for 8 weeks to make arsenic model and upon these arsenic pretreated rats Emblica officinalis was administered for 4 weeks to study the antidote effects of this plant. The plant not only eliminated the effects of arsenic but also reversed the normal physiological activity in the animal by normalising the activity of liver and kidney. The present study concludes that this novel plant possesses hepato-protective as well as nephron-protective activity against arsenic induced toxicity.

Keywords: Sodium Arsenite; Emblica Officinalis; Antidote Effect; Rats (search for similar items in EconPapers)
Date: 2015
References: View complete reference list from CitEc
Citations:

Downloads: (external link)
https://www.ijsciences.com/pub/article/652 (text/html)
https://www.ijsciences.com/pub/pdf/V420150328.pdf (application/pdf)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:adm:journl:v:4:y:2015:i:3:p:47-55

Ordering information: This journal article can be ordered from
https://www.ijsciences.com/payment_guide.php

DOI: 10.18483/ijSci.652

Access Statistics for this article

More articles in International Journal of Sciences from Office ijSciences Alkhaer Publications Manchester M8 8XG England.
Bibliographic data for series maintained by Staff ijSciences ().