The Influence of Perineural Invation on the Prognosis of Patients with Gastric Cancer after Radical Operation _A Retrospective Study

Houxin Zhu, Lin Sun and Tuo Shi

International Journal of Sciences, 2018, vol. 7, issue 11, 30-34

Abstract: Objective to investigate the influence of perineural invation (PNI) on the prognosis of patients with gastric cancer after radical resection. Method: we collected 278 patients in Affiliated Hospital of Qingdao University with gastric cancer after radical operation and to analysis. The specimens of gastric cancer were stained with hematoxylin and eosin (HE), when the tumor cells were infiltrated the membrane or the nerve bundles, it would be defined as PNI positive. To analyzed the relationship between PNI and other clinic-pathological features and the influence of prognosis. Results: The 5-year overall survival of the patients with PNI were lower than those of the patients with negative perineural infiltration (26.45% vs 43.72%, P 0.05). Conclusion: patients with PNI positive with lower rate of survival. PNI positive is related to the progression of gastric cancer.

Keywords: Gastric Cancer; Perineural Infiltration; Radical Operation; Prognosis (search for similar items in EconPapers)
Date: 2018
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DOI: 10.18483/ijSci.1827

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