Urine Lunx mRNA as a Potential Molecular Diagnostic Tool for Lung Cancer

Sanxia Zhao and Yinlin Ge

International Journal of Sciences, 2018, vol. 7, issue 09, 1-3

Abstract: Objective: Exploring the expression of cell-free RNA in urine of normal patients and lung cancer patients, analyze its clinical value in the dignosis of lung cancer. Methods: The urine samples were collected from lung cancer patients and healthy people. Extracted the total cf-RNA from all samples. The contents of total cf-RNA in two groups were detected, and the expressions of LUNX mRNA in two groups were measured by quantitative real-time PCR. Receiver-operating characteristics (ROC) curve was established to evaluate the diagnostic value of urine cf-RNA for the differentiation between lung cancer patients and the control group. Results: Compare to the normal group (50.50±4.527ng), the urinary cf-RNA content in patients (133.8±8.615ng) was significantly increased, p

Keywords: Urine; Lung Cancer; cf-RNA; Diagnosis (search for similar items in EconPapers)
Date: 2018
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DOI: 10.18483/ijSci.1782

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