Research Progress of Antitumor Activity by Baicalin and Baicalein

Wang Yu and Li Ling

International Journal of Sciences, 2019, vol. 8, issue 06, 11-14

Abstract: Baicalin and its aglycon, baicalein, are flavonoids present from Scutellaria baicalensis Georgi. Baicalin generally inhibits tumor cells by inducing apoptosis and arresting growth, while baicalein suppresses by regulating autophagy. Certain signaling pathways and regulating factors are involved among the induced-apoptosis and autophagy progress. In suppressing growth, baicalin and baicaein inhibit angiogenesis or induce cell cycle arrest at S phase against proliferation, migration and differentiation. The present agents against tumor still have related side effects. Therefore, the natural and nontoxic flavonoids are promising in present even future tumor treatment.

Keywords: Antitumor; Baicalin; Baicalein (search for similar items in EconPapers)
Date: 2019
References: View complete reference list from CitEc
Citations:

Downloads: (external link)
https://www.ijsciences.com/pub/article/2099 (text/html)
https://www.ijsciences.com/pub/pdf/V82019062099.pdf (application/pdf)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:adm:journl:v:8:y:2019:i:6:p:11-14

Ordering information: This journal article can be ordered from
https://www.ijsciences.com/payment_guide.php

DOI: 10.18483/ijSci.2099

Access Statistics for this article

More articles in International Journal of Sciences from Office ijSciences Alkhaer Publications Manchester M8 8XG England.
Bibliographic data for series maintained by Staff ijSciences ().