Dedifferentiated Chondrosarcoma of the Larynx A Case Report and Review of the Literature

Kelsey C Hinther and Rick Jaggi
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Kelsey C Hinther: College of Medicine, University of Saskatchewan, Canada
Rick Jaggi: Division of Otolaryngology, University of Saskatchewan, Canada

International Journal of Cell Science & Molecular Biology, 2018, vol. 4, issue 2, 25-31

Abstract: Laryngeal chondrosarcomas are rare, slow-growing, cartilaginous tumors. Dedifferentiated chondrosarcomas, a rare entity of chondrosarcoma, are more aggressive and associated with a more ominous prognosis. Definite diagnosis can be established by incisional biopsy and histopathologic examination. Histopathologic examination reveals a cartilaginous tumor with a malignant spindle cell component. Definitive reatment of dedifferentiated chondrosarcomas of the larynx is total laryngectomy. There have been 14 case reports of laryngeal dedifferentiated chondrosarcoma reported since 1988. The average life expectancy reported is 6 months, and a 5-year survival rate of 10.5%.

Keywords: juniper publishers; Journal of Cell Science; Molecular Biology; International Journal of Cell Science; International Journal of Cell Science & Molecular Biology; molecular biology journals list; molecular biology impact factor; molecular biology scholarly journal; molecular biology online journals; molecular biology research papers; scientific journals; juniper publishers review (search for similar items in EconPapers)
Date: 2018
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Persistent link: https://EconPapers.repec.org/RePEc:adp:ijcsmb:v:4:y:2018:i:2:p:25-31

DOI: 10.19080/IJCSMB.2018.03.555631

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