High Risk HPV, HSIL and Primary Diffuse Large B Cell Lymphoma of Cervix: An Unsual Case

Sreekala Sreehari, Mohanad Diab and Paulina Manosalvas Martinez
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Sreekala Sreehari: Department of Histopathology, NMC Royal Hospital, UAE
Mohanad Diab: Department of Medical oncology, NMC Royal Hospital, UAE
Paulina Manosalvas Martinez: Department of Obstetrics and Gynecology, NMC Royal Hospital, UAE

International Journal of Cell Science & Molecular Biology, 2019, vol. 5, issue 4, 71-73

Abstract: Primary malignant non-Hodgkin’s lymphomas in the female genital tract are rare, accounting for less than 1% of all extranodal non-Hodgkin’s lymphomas. HPV infection has well been documented as the causative factor for Carcinoma cervix; not malignant lymphoma of cervix. Here we report an interesting case of primary non-Hodgkin’s lymphomas of uterine cervix with proven HPV 16 infection and High grade squamous intraepithelial lesion with co-existing diffuse large B-cell lymphomas (DLBCL) on histopathological examination and immunohistochemical study. The patient was successfully treated with chemotherapy after Cervical Conisation for HSIL and is now in complete remission with follow up period of 11 months. Gynecological lymphomas can be a diagnostic challenge due to nonspecific symptoms. However, when diagnosed and treated they have a good prognosis. Clinicians should therefore include lymphoma in their differential diagnosis when investigating gynecological symptoms.

Keywords: juniper publishers; Journal of Cell Science; Molecular Biology; International Journal of Cell Science; International Journal of Cell Science & Molecular Biology; molecular biology journals list; molecular biology impact factor; molecular biology scholarly journal; molecular biology online journals; molecular biology research papers; scientific journals; juniper publishers review (search for similar items in EconPapers)
Date: 2019
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Persistent link: https://EconPapers.repec.org/RePEc:adp:ijcsmb:v:5:y:2019:i:4:p:71-73

DOI: 10.19080/IJCSMB.2019.04.555666

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