MazEF homologous Modules System and A Post-segregational killing Mechanism (Bacteriostatic & Bactericidal Mechanism) of Novel Compound Isolated from Spondias monbinon Escherichia Coli and Bacillus Subtilis

Oludare Temitope Osuntokun, Olaposi A Omotuyi and Anthonia O Oluduro
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Oludare Temitope Osuntokun: Department of Microbiology, Adekunle Ajasin University, Nigeria
Olaposi A Omotuyi: Centre for Biocomputing and Drug Development (CBDD), Adekunle Ajasin University, Nigeria
Anthonia O Oluduro: ubmission: February 14, 2019; Published: March 08, 2019

International Journal of Cell Science & Molecular Biology, 2019, vol. 5, issue 5, 101-109

Abstract: The basic objective of this research work is to evaluate the mechanism of action of compound Epigallocatechin, Epicatechin and Stigmasterol Phytosterol (Synergy), Aspidofractinine-3-methanol) and Terephthalic acid, dodecyl 2-ethylhexyl ester with Selected clinical isolates by using molecular biomarker MazEF9 TA system. Toxin-Antitoxin (TA) systems are highly conserved in members of the Gram positive +ve and Gram negative –ve bacteria which has been proposed to play an important role in physiology and virulence. Clinical microorganisms were cultured and Sub-culturing in Department of Microbiology and Centre for Biocomputing and Drug Development (CBDD), Adekunle Ajasin University, Akungba Akoko, Ondo-state, Nigeria. A 12 hours old culture of each microorganism was re-suspended in plant extract at 1000 μg mL in a total volume of 500μl for 0, 15, 30, 45, 60, and 180 minutes.

Keywords: juniper publishers; Journal of Cell Science; Molecular Biology; International Journal of Cell Science; International Journal of Cell Science & Molecular Biology; molecular biology journals list; molecular biology impact factor; molecular biology scholarly journal; molecular biology online journals; molecular biology research papers; scientific journals; juniper publishers review (search for similar items in EconPapers)
Date: 2019
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Persistent link: https://EconPapers.repec.org/RePEc:adp:ijcsmb:v:5:y:2019:i:5:p:101-109

DOI: 10.19080/IJCSMB.2019.04.555673

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