A Neutrophil’s Perspective: the Innate Response to Tuberculosis Infection and the Induction of Adaptive Immunity

Lorinda du Toit, Willem J du Plessis and Andre G Loxton
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Lorinda du Toit: SA MRC Centre for TB Research, Stellenbosch University, South Africa
Willem J du Plessis: SA MRC Centre for TB Research, Stellenbosch University, South Africa
Andre G Loxton: SA MRC Centre for TB Research, Stellenbosch University, South Africa

International Journal of Pulmonary & Respiratory Sciences, 2017, vol. 1, issue 3, 79-89

Abstract: Neutrophils were traditionally viewed as short lived, terminal, innate effector cells that eliminate microbes and remove cellular debris at the site of infection or inflammation. They mediate this by phagocytosis, the release of reactive oxygen species, antimicrobial proteins and proteolytic enzymes. During recent years, studies have demonstrated that they are longer lived than initially thought and they mediate a large number of immune functions by the release of a variety of preformed and newly synthesized molecules such as cytokines and chemokines.

Keywords: uniper publishers:International Journal of Pulmonary; Journal of Pulmonary Sciences; Journal of Pulmonary & Respiratory Sciences; Pulmonary & Respiratory Sciences; pulmonary & respiratory medicine open access journals; pulmonary & respiratory medicine impact factor journals; pulmonary & respiratory medicine peer review journals; chronic obstructive pulmonary disease; pulmonary arterial hypertension impact factor journals; pulmonary aspergillosis high impact factor journals (search for similar items in EconPapers)
Date: 2017
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Persistent link: https://EconPapers.repec.org/RePEc:adp:ijoprs:v:1:y:2017:i:3:p:79-89

DOI: 10.19080/IJOPRS.2017.01.555563

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