In Vitro Preparation of H2O2 Inactivated Rabies Vaccine and Related Immunogenicity

Kareem Essam, Reham Mohsen, Eman Amin Ismail and Kareem Mohamed
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Kareem Essam: Faculty of biotechnology, October university of Modern Science and Arts, Egypt
Reham Mohsen: Faculty of biotechnology, October university of Modern Science and Arts, Egypt
Eman Amin Ismail: The International Center for Advanced Researchers (ICTAR-Egypt), Egypt

International Journal of Pulmonary & Respiratory Sciences, 2018, vol. 3, issue 4, 69-76

Abstract: The aim of the present work is to produce local H2O2 inactivated vaccine and monitor its quality to the currently available in the Egyptian market. Data revealed that H2O2 could inactivate rabies virus within 3 hrs. Produced vaccine potency was evaluated using mice inoculation assay indicating that the ED50 of test vaccine was >2.5 IU according to the WHO regulation.

Keywords: uniper publishers:International Journal of Pulmonary; Journal of Pulmonary Sciences; Journal of Pulmonary & Respiratory Sciences; Pulmonary & Respiratory Sciences; pulmonary & respiratory medicine open access journals; pulmonary & respiratory medicine impact factor journals; pulmonary & respiratory medicine peer review journals; chronic obstructive pulmonary disease; pulmonary arterial hypertension impact factor journals; pulmonary aspergillosis high impact factor journals (search for similar items in EconPapers)
Date: 2018
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Persistent link: https://EconPapers.repec.org/RePEc:adp:ijoprs:v:3:y:2018:i:4:p:69-76

DOI: 10.19080/IJOPRS.2018.03.555619

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