A Novel Approach to Developing in Vitro Culture Method for Enhancing Anti-Cancer Nature of ADMSCs

Jeong Chan Ra
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Jeong Chan Ra: Biostar Stem Cell Research Institute, Republic of Korea

Current Trends in Biomedical Engineering & Biosciences, 2018, vol. 11, issue 4, 78-79

Abstract: Cell therapies using adult stem cells have been shown to be efficacious in many diseases that cannot be treated effectively by conventional treatment methods and are widely being used already in every day clinical settings across the globe. Nevertheless, worries about possible cancer-related issues make us reluctant to use stem cell therapies proactively. Controversial results were reported that stem cell therapies either promoted or inhibited cancers in vitro or in animal models. Therefore, it is important to study the culture- method of AdMSCs inhibiting cancer development and not promoting cancer. We are currently developing in vitro culture methods of enhancing this anti-cancer function of AdMSCs. During the culture process of stem cells, a certain factor was added to the culture media to identify the specific factor showing anticancer property, and the efficacy of anticancer-stem cells was confirmed in vitro. Additionally, by checking the profiles of cancer markers, we confirmed cancers were not occurred among the patients who had received multiple intravenous infusions of the autologous stem cells cultured in the media containing a factor of enhancing anticancer property, vitamin C. Based on our evidences, we believe that the differences of culture milieu for AdMSCs in vitro can either promote or inhibit cancers according to their media properties.

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Date: 2018
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Persistent link: https://EconPapers.repec.org/RePEc:adp:jctbeb:v:11:y:2018:i:4:p:78-79

DOI: 10.19080/CTBEB.2018.11.555818

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