Protein Disulfide Isomerase: A New Class of Drug Target

Noureddine Ben Khalaf and M Dahmani Fathallah
Additional contact information
M Dahmani Fathallah: Department of Life Sciences, Arabian Gulf University, Manama, Bahrain

Current Trends in Biomedical Engineering & Biosciences, 2018, vol. 12, issue 2, 64-67

Abstract: Protein Disulfide Isomerase (PDI) was originally discovered fifty years ago as the first protein folding catalyst and isolated from rat liver [1]. It was demonstrated early on that PDI acts as a dithiol–disulfide oxidoreductase capable of reducing, oxidizing and isomerizing disulfide bonds. Independently of its redox activity, PDI can also act as a vital cellular defense against the intracellular accumulation of misfolded proteins via its chaperone activity [2].

Keywords: juniper publishers group; juniper publishers Biomedical Engineering journals; Biomedical Engineering journals list; medical devices journals; peer reviewed Biomedical Engineering journals; open access Biomedical Engineering journals; Biomedical Engineering journals impact factor; Biomedical Engineering scientific journals; Biomedical Engineering articles; scholarly Biomedical Engineering journals; juniper publishers reivew (search for similar items in EconPapers)
Date: 2018
References: View complete reference list from CitEc
Citations:

Downloads: (external link)
https://juniperpublishers.com/ctbeb/pdf/CTBEB.MS.ID.555838.pdf (application/pdf)
https://juniperpublishers.com/ctbeb/CTBEB.MS.ID.555838.php (text/html)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:adp:jctbeb:v:12:y:2018:i:2:p:64-67

DOI: 10.19080/CTBEB.2018.12.555838

Access Statistics for this article

Current Trends in Biomedical Engineering & Biosciences is currently edited by Sophia Mathis

More articles in Current Trends in Biomedical Engineering & Biosciences from Juniper Publishers Inc.
Bibliographic data for series maintained by Robert Thomas ().