Hybrid Approach of Hyperthermia and Controlled Drug Delivery in Cancer: Image Guided Cancer Theranostic Monitoring in Tumor Management

Rakesh Sharma
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Rakesh Sharma: Innovations and Solutions Inc, Florida State University Research Foundation, USA

Cancer Therapy & Oncology International Journal, 2018, vol. 11, issue 1, 16-27

Abstract: Nonpathogenic bacteria coats filled with complex metal nanoparticles form multifunctional magnetic nanoparticles (MNPs) for targeting cancer tumors. The encapsulated metal nanoparticles along with anticancer drugs inside polymer or bacterial coats become physiologically tumor sensitive due to hysteresis and pH sensitivity and drug active covalent bonds. Drug-bearing bacterial and polymer nanoshells open and close at specific pH to release anticancer drugs in controlled manner at the tumor sites. Simultaneously, metal core generates multimodal images. Such combined effect of chemotherapy and tumor sensitive nanodrugs offers hybrid approach of an effective and minimal invasive protocol of tumor management.

Keywords: juniper publishers:oncology journals; oncology research journals; oncology journal articles; oncology and cancer case reports; oncology journal of clinical and experimental cancer research; open access; open access journals; Oncology International Journal; juniper publishers reivew (search for similar items in EconPapers)
Date: 2018
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Persistent link: https://EconPapers.repec.org/RePEc:adp:jctoij:v:11:y:2018:i:1:p:16-27

DOI: 10.19080/CTOIJ.2018.11.555803

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